Modeling the potential health impact of prospective Strep A vaccines

Modeling the potential health impact of prospective Strep A vaccines

Blog Article

Abstract The World Health Organization published the preferred product characteristics for a Group A Streptococcus (Strep A) vaccine in 2018.Based on these parameters for the age of vaccination, vaccine efficacy, duration of protection from vaccine-derived immunity, and vaccination coverage, we developed a static cohort model to estimate the projected health impact of Strep good news candy A vaccination at the global, regional, and national levels and by country-income category.We used the model to analyse six strategic scenarios.Based on Strep A vaccine introduction between 2022 and 2034 for the primary scenario, we estimated vaccination at birth for 30 vaccinated cohorts could avert 2.

5 army meritorious civilian service medal billion episodes of pharyngitis, 354 million episodes of impetigo, 1.4 million episodes of invasive disease, 24 million episodes of cellulitis, and 6 million cases of rheumatic heart disease globally.Vaccination impact in terms of burden averted per fully vaccinated individual is highest in North America for cellulitis and in Sub-Saharan Africa for rheumatic heart disease.